Rob Holding makes the trip, having not yet made an appearance on the comeback trail from a serious knee injury.
Also featuring in Emery’s 19-man squad are youngsters Joe Willock, Bukayo Saka, Reiss Nelson and Emile Smith-Rowe.
Thursday’s game in Germany kicks off at 5.55pm UK time, with Group F rivals Standard Liege and Vitoria facing off in Belgium the same night.
Arsenal vs Eintracht Frankfurt squad:
Goalkeepers – Leno, Martinez.
Defenders – Maitland-Niles, Chambers, Mustafi, Holding, Luiz, Kolasinac.
Midfielders – Guendouzi, Torreira, Willock, Xhaka, Ceballos, Smith Rowe.
Attackers – Martinelli, Nelson, Pepe, Saka, Aubameyang.